Childhood Obesity: Understanding and Preventing
Doctors say that obesity is now reaching ‘epidemic’ proportions. According to recent figures from the National Child Measurement Programme, which assesses height and weight of children in England, more than 33% of 11-year-olds and 22% of 4- and 5-year-olds are overweight or obese. Being overweight is linked to numerous health problems, including diabetes, heart disease and high blood pressure, as well as psychological problems, such as stress, anxiety and depression. Unfortunately, parents struggle with many problems when it comes to managing their children’s weight (i.e. lack of education about healthy eating, lack of cooking skills, financial problems, marketing campaigns for junk food). It therefore seems that one’s environment plays an important role in becoming obese.
However, do only environmental factors lead to obesity?
Researchers at the Wellcome Trust-MRC Institute of Metabolic Science (University of Cambridge, Metabolic Research Laboratories) studied a cohort of children with extreme obesity from an early age and discovered that a number of gene mutations are directly linked with obesity. All of these genes are found in the hypothalamus, which is the region of the brain that is responsible for controlling appetite and food intake. These findings do not only indicate that obesity is biologically driven but also amenable to mechanism-based therapy. In fact, one gene defect is dramatically curable with daily injections of a protein called leptin.
Understanding obesity can hopefully open doors to research for prevention!
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For more information:
http://www.neuroscience.cam.ac.uk/research/cameos/ObeseBrain.php